In reality those software's do different things and thus are not exclusive. 3D and 2D modes and then it's also officially even 2.5D program and many have not even heard what that means 'to be in 2.5D'
The difficulty of Zbrush is that it uses 2 modes. With 3D or 2.5D you are not taking any shortcuts and no program is easy to use. So to sum up you must ask from yourself what you want to achieve and pick tools based on that. Sculptris is like a Toddler sister of Zbrush, while Zbrush is a already a working adult. And you should take time to master its tools if you want to do top notch sculpts. ZBrush has very unique controls because of the nature of the software, but it's industry standard for a reason. It's like acting what you like more apples or bananas instead asking which brand of apple is best. And Blender is a 3D MODELLING program and Vue is another thing completely. Zbrush is a 3D and 2.5D program or sculpting program. 1st they are not even remotely same 'thing'.
